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1

A scalable and reproducible manufacturing process for Phlebotomus papatasi salivary protein PpSP15, a vaccine candidate for leishmaniasis

Liu, Zhuyun, Kundu, Rakhi, Damena, Surafel, Biter, Amadeo B., Nyon, Mun Peak, Chen, Wen-Hsiang, Zhan, Bin, Strych, Ulrich, Hotez, Peter J., Bottazzi, Maria Elena

Journal:

Protein Expression and Purification

Year:

2021

File:

PDF, 2.64 MB

2021

2

Establishing Preferred Product Characterization for the Evaluation of RNA Vaccine Antigens

Poveda, Cristina, Biter, Amadeo B., Bottazzi, Maria Elena, Strych, Ulrich

Journal:

Year:

2019

Language:

english

File:

PDF, 895 KB

english, 2019

3

A method to probe protein structure from UV absorbance spectra

Biter, Amadeo B., Pollet, Jeroen, Chen, Wen-Hsiang, Strych, Ulrich, Hotez, Peter J., Bottazzi, Maria Elena

Journal:

Analytical Biochemistry

Year:

2019

Language:

english

File:

PDF, 1.60 MB

english, 2019

4

Vaccine Efficacy Needed for a COVID-19 Coronavirus Vaccine to Prevent or Stop an Epidemic as the Sole Intervention

Bartsch, Sarah M., O'Shea, Kelly J., Ferguson, Marie C., Bottazzi, Maria Elena, Wedlock, Patrick T., Strych, Ulrich, McKinnell, James A., Siegmund, Sheryl S., Cox, Sarah N., Hotez, Peter J., Lee, Bruc

Journal:

American Journal of Preventive Medicine

Year:

2020

File:

PDF, 1.31 MB

2020

5

New Vaccines for the World’s Poorest People

Hotez, Peter J., Bottazzi, Maria Elena, Strych, Ulrich

Journal:

Annual Review of Medicine

Year:

2016

Language:

english

File:

PDF, 593 KB

english, 2016

6

Neglected Tropical Diseases among the Association of Southeast Asian Nations (ASEAN): Overview and Update

Hotez, Peter J., Bottazzi, Maria Elena, Strych, Ulrich, Chang, Li-Yen, Lim, Yvonne A. L., Goodenow, Maureen M., AbuBakar, Sazaly, Gray, Darren J.

Journal:

PLoS Neglected Tropical Diseases

Year:

2015

Language:

english

File:

PDF, 563 KB

english, 2015

7

Protective immunity elicited by the nematode-conserved As37 recombinant protein against Ascaris suum infection

Versteeg, Leroy, Wei, Junfei, Liu, Zhuyun, Keegan, Brian, Fujiwara, Ricardo T., Jones, Kathryn M., Asojo, Oluwatoyin, Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J., Zhan, Bin, Diemert, David

Journal:

PLoS Neglected Tropical Diseases

Year:

2020

File:

PDF, 1.99 MB

2020

8

Functionalized viral nanoparticles as ultrasensitive reporters in lateral-flow assays

Adhikari, Meena, Dhamane, Sagar, Hagström, Anna E. V., Garvey, Gavin, Chen, Wen-Hsiang, Kourentzi, Katerina, Strych, Ulrich, Willson, Richard C.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2013

Language:

english

File:

PDF, 353 KB

english, 2013

9

Status of vaccine research and development of vaccines for leishmaniasis

Gillespie, Portia M., Beaumier, Coreen M., Strych, Ulrich, Hayward, Tara, Hotez, Peter J., Bottazzi, Maria Elena

Journal:

Year:

2016

Language:

english

File:

PDF, 437 KB

english, 2016

10

Ultrasensitive immuno-detection using viral nanoparticles with modular assembly using genetically-directed biotinylation

Litvinov, Julia, Hagström, Anna E. V., Lopez, Yubitza, Adhikari, Meenu, Kourentzi, Katerina, Strych, Ulrich, Monzon, Federico A., Foster, William, Cagle, Philip T., Willson, Richard C.

Journal:

Biotechnology Letters

Year:

2014

Language:

english

File:

PDF, 314 KB

english, 2014

11

COVID-19 vaccines: neutralizing antibodies and the alum advantage

Hotez, Peter J., Corry, David B., Strych, Ulrich, Bottazzi, Maria Elena

Journal:

Nature Reviews Immunology

Year:

2020

File:

PDF, 440 KB

2020

12

Characterization of the alanine racemases from two Mycobacteria

Ulrich Strych, Rebecca L Penland, Margarita Jimenez, Kurt L Krause, Michael J Benedik

Journal:

FEMS Microbiology Letters

Year:

2001

Language:

english

File:

PDF, 354 KB

english, 2001

13

Crystal Structure at 1.45 Å Resolution of Alanine Racemase from a Pathogenic Bacterium, Pseudomonas aeruginosa , Contains Both Internal and External Aldimine Forms †,‡

LeMagueres, Pierre, Im, Hookang, Dvorak, Anna, Strych, Ulrich, Benedik, Michael, Krause, Kurt L.

Journal:

Year:

2003

Language:

english

File:

PDF, 1.12 MB

english, 2003

14

Characterization and stability of Trypanosoma cruzi 24-C4 (Tc24-C4), a candidate antigen for a therapeutic vaccine against Chagas disease

Biter, Amadeo B., Weltje, Sarah, Hudspeth, Elissa M., Seid, Christopher A., McAtee, C. Patrick, Chen, Wen-Hsiang, Pollet, Jeroen B., Strych, Ulrich, Hotez, Peter J., Bottazzi, Maria Elena

Journal:

Journal of Pharmaceutical Sciences

Year:

2017

Language:

english

File:

PDF, 4.39 MB

english, 2017

15

A peroxidase-active aptazyme as an isothermally amplifiable label in an aptazyme-linked oligonucleotide assay for low-picomolar IgE detection

Pollet, Jeroen, Strych, Ulrich, Willson, Richard C.

Journal:

The Analyst (Royal Society of Chemistry)

Year:

2012

Language:

english

File:

PDF, 282 KB

english, 2012

16

Covalent vaccination with Trypanosoma cruzi Tc24 induces catalytic antibody production

Gunter, Sarah M., Versteeg, Leroy, Jones, Kathryn M., Brian, Keegan P, Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J., Brown, Eric L.

Journal:

Parasite Immunology

Year:

2018

File:

PDF, 565 KB

2018

17

Process Characterization and Biophysical Analysis for a Yeast-expressed Phlebotomus papatasi Salivary Protein (PpSP15) as a Leishmania vaccine candidate

Chen, Wen-Hsiang, Nyon, Mun-peak, Poongavanam, Mohan V., Liu, Zhuyun, Biter, Amadeo B., Kundu, Rakhi T., Strych, Ulrich, Hotez, Peter J., Bottazzi, Maria Elena

Journal:

Journal of Pharmaceutical Sciences

Year:

2020

Language:

english

File:

PDF, 1.48 MB

english, 2020

18

Purification and preliminary crystallization of alanine racemase fromStreptococcus pneumoniae

Ulrich Strych, Milya Davlieva, Joseph P Longtin, Eileen L Murphy, Hookang Im, Michael J Benedik, Kurt L Krause

Journal:

BMC Microbiology

Year:

2007

Language:

english

File:

PDF, 653 KB

english, 2007

19

Characterization of the alanine racemases from two Mycobacteria

Ulrich Strych, Rebecca L Penland, Margarita Jimenez, Kurt L Krause, Michael J Benedik

Journal:

FEMS Microbiology Letters

Year:

2001

Language:

english

File:

PDF, 357 KB

english, 2001

20

Serratia marcescens and its extracellular nuclease

Michael J Benedik, Ulrich Strych

Journal:

FEMS Microbiology Letters

Year:

1998

Language:

english

File:

PDF, 1.00 MB

english, 1998

21

Biochemical and structural characterization of alanine racemase fromBacillus anthracis(Ames)

Rafael M Couñago, Milya Davlieva, Ulrich Strych, Ryan E Hill, Kurt L Krause

Journal:

BMC Structural Biology

Year:

2009

Language:

english

File:

PDF, 1.91 MB

english, 2009

22

Label-free, in situ SERS monitoring of individual DNA hybridization in microfluidics

Qi, Ji, Zeng, Jianbo, Zhao, Fusheng, Lin, Steven Hsesheng, Raja, Balakrishnan, Strych, Ulrich, Willson, Richard C., Shih, Wei-Chuan

Journal:

Year:

2014

Language:

english

File:

PDF, 1.13 MB

english, 2014

23

N(2)-Substituted D,L-Cycloserine Derivatives: Synthesis and Evaluation as Alanine Racemase Inhibitors.

Myoung Goo Kim, Ulrich Strych, Kurt Krause, Michael Benedik, Harold Kohn

Journal:

Year:

2003

File:

PDF, 68 KB

2003

24

Status of vaccine research and development of vaccines for Chagas disease

Beaumier, Coreen M., Gillespie, Portia M., Strych, Ulrich, Hayward, Tara, Hotez, Peter J., Bottazzi, Maria Elena

Journal:

Year:

2016

Language:

english

File:

PDF, 591 KB

english, 2016

25

A simple fluorescence-based assay for quantification of the Toll-Like Receptor agonist E6020 in vaccine formulations

Pollet, Jeroen, Versteeg, Leroy, Rezende, Wanderson, Strych, Ulrich, Gusovsky, Fabian, Hotez, Peter J., Bottazzi, Maria Elena

Journal:

Year:

2017

Language:

english

File:

PDF, 1.45 MB

english, 2017

26

Vaccine Development Against Middle East Respiratory Syndrome

Hai Yen Lee,Mun Peak Nyon,Ulrich Strych

Journal:

Current Tropical Medicine Reports

Year:

2016

Language:

english

File:

PDF, 314 KB

english, 2016

27

N(2)-Substituted D,L-Cycloserine Derivatives: Synthesis and Evaluation as Alanine Racemase Inhibitors.

KIM, MYOUNG GOO, STRYCH, ULRICH, KRAUSE, KURT, BENEDIK, MICHAEL, KOHN, HAROLD

Journal:

The Journal of Antibiotics

Year:

2003

Language:

english

File:

PDF, 1.15 MB

english, 2003

28

The potential economic value of a therapeutic Chagas disease vaccine for pregnant women to prevent congenital transmission

Bartsch, Sarah M., Stokes-Cawley, Owen J., Buekens, Pierre, Asti, Lindsey, Bottazzi, Maria Elena, Strych, Ulrich, Wedlock, Patrick T., Mitgang, Elizabeth A., Meymandi, Sheba, Falcon-Lezama, Jorge Abel

Journal:

Year:

2020

File:

PDF, 869 KB

2020

29

Characterization of the Alanine Racemases fromPseudomonas aeruginosaPAO1

Ulrich Strych, Hung-Chung Huang, Kurt L. Krause, Michael J. Benedik

Journal:

Current Microbiology

Year:

2000

Language:

english

File:

PDF, 190 KB

english, 2000

30

Advancing a vaccine to prevent hookworm disease and anemia

Hotez, Peter J., Beaumier, Coreen M., Gillespie, Portia M., Strych, Ulrich, Hayward, Tara, Bottazzi, Maria Elena

Journal:

Year:

2016

Language:

english

File:

PDF, 720 KB

english, 2016

31

Advancing a vaccine to prevent human schistosomiasis

Merrifield, Maureen, Hotez, Peter J., Beaumier, Coreen M., Gillespie, Portia, Strych, Ulrich, Hayward, Tara, Bottazzi, Maria Elena

Journal:

Year:

2016

Language:

english

File:

PDF, 254 KB

english, 2016

32

The SARS-CoV-2 Vaccine Pipeline: an Overview

Chen, Wen-Hsiang, Strych, Ulrich, Hotez, Peter J, Bottazzi, Maria Elena

Journal:

Current Tropical Medicine Reports

Year:

2020

File:

PDF, 239 KB

2020

33

New Classes of Alanine Racemase Inhibitors Identified by High-Throughput Screening Show Antimicrobial Activity against Mycobacterium tuberculosis

Anthony, Karen G., Strych, Ulrich, Yeung, Kacheong R., Shoen, Carolyn S., Perez, Oriana, Krause, Kurt L., Cynamon, Michael H., Aristoff, Paul A., Koski, Raymond A., Ahmed, Niyaz

Journal:

Year:

2011

Language:

english

File:

PDF, 635 KB

english, 2011

34

DNAzyme-mediated recovery of small recombinant RNAs from a 5S rRNA-derived chimera expressed inEscherichia coli

Yamei Liu, Victor G Stepanov, Ulrich Strych, Richard C Willson, George W Jackson, George E Fox

Journal:

BMC Biotechnology

Year:

2010

Language:

english

File:

PDF, 754 KB

english, 2010

35

Flotation Immunoassay: Masking the Signal from Free Reporters in Sandwich Immunoassays

Chen, Hui, Hagström, Anna E. V., Kim, Jinsu, Garvey, Gavin, Paterson, Andrew, Ruiz-Ruiz, Federico, Raja, Balakrishnan, Strych, Ulrich, Rito-Palomares, Marco, Kourentzi, Katerina, Conrad, Jacinta C., A

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.32 MB

english, 2016

36

Orotidine-5′-monophosphate decarboxylase fromPseudomonas aeruginosaPAO1: Cloning, overexpression, and enzyme characterization

Ulrich Strych, Susanne Wohlfarth, Ulrich K. Winkler

Journal:

Current Microbiology

Year:

1994

Language:

english

File:

PDF, 850 KB

english, 1994

37

Human anthelminthic vaccines: Rationale and challenges

Hotez, Peter J., Strych, Ulrich, Lustigman, Sara, Bottazzi, Maria Elena

Journal:

Year:

2016

Language:

english

File:

PDF, 878 KB

english, 2016

38

Yeast-expressed recombinant As16 protects mice against Ascaris suum infection through induction of a Th2-skewed immune response

Wei, Junfei, Versteeg, Leroy, Liu, Zhuyun, Keegan, Brian, Gazzinelli-Guimarães, Ana Clara, Fujiwara, Ricardo T., Briggs, Neima, Jones, Kathryn M., Strych, Ulrich, Beaumier, Coreen M., Bottazzi, Maria

Journal:

PLoS Neglected Tropical Diseases

Year:

2017

Language:

english

File:

PDF, 5.20 MB

english, 2017

39

Yeast-expressed SARS-CoV recombinant receptor-binding domain (RBD219-N1) formulated with aluminum hydroxide induces protective immunity and reduces immune enhancement

Chen, Wen-Hsiang, Tao, Xinrong, Agrawal, Anurodh Shankar, Algaissi, Abdullah, Peng, Bi-Hung, Pollet, Jeroen, Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J., Lustigman, Sara, Du, Lanying, Jiang

Journal:

Year:

2020

File:

PDF, 33 KB

2020

40

Engineered 5S ribosomal RNAs displaying aptamers recognizing vascular endothelial growth factor and malachite green

Xing Zhang, Ajish S. R. Potty, George W. Jackson, Victor Stepanov, Andrew Tang, Yamei Liu, Katerina Kourentzi, Ulrich Strych, George E. Fox, Richard C. Willson

Journal:

Journal of Molecular Recognition

Year:

2009

Language:

english

File:

PDF, 430 KB

english, 2009

41

Rare target enrichment for ultrasensitive PCR detection using cot–rehybridization and duplex-specific nuclease

Charul Gijavanekar, Ulrich Strych, Yuriy Fofanov, George E. Fox, Richard C. Willson

Journal:

Analytical Biochemistry

Year:

2012

Language:

english

File:

PDF, 329 KB

english, 2012

42

Coronavirus vaccine-associated lung immunopathology-what is the significance?

Bottazzi, Maria Elena, Strych, Ulrich, Hotez, Peter J., Corry, David B.

Journal:

Microbes and Infection

Year:

2020

File:

PDF, 165 KB

2020

43

Mutations to Cysteine Residues in the Trypanosoma cruzi B-Cell Superantigen Tc24 Diminish Susceptibility to IgM-Mediated Hydrolysis

Gunter, Sarah M., Jones, Kathryn M., Seid, Christopher A., Essigmann, Heather T., Zhan, Bin, Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J., Brown, Eric L.

Journal:

Journal of Parasitology

Year:

2017

Language:

english

File:

PDF, 516 KB

english, 2017

44

Covalent vaccination with Trypanosoma cruzi Tc24 induces catalytic antibody production

Gunter, Sarah M., Versteeg, Leroy, Jones, Kathryn M., Brian, Keegan P, Strych, Ulrich, Bottazzi, Maria Elena, Hotez, Peter J., Brown, Eric L.

Journal:

Parasite Immunology

Year:

2018

Language:

english

File:

PDF, 565 KB

english, 2018

45

Detection and Typing of Viruses Using Broadly Sensitive Cocktail-PCR and Mass Spectrometric Cataloging

Gijavanekar, Charul, Drabek, Rafal, Soni, Mithil, Jackson, George W., Strych, Ulrich, Fox, George E., Fofanov, Yuriy, Willson, Richard C.

Journal:

The Journal of Molecular Diagnostics

Year:

2012

Language:

english

File:

PDF, 407 KB

english, 2012

46

Economic value of a therapeutic Chagas vaccine for indeterminate and Chagasic cardiomyopathy patients

Bartsch, Sarah M., Bottazzi, Maria Elena, Asti, Lindsey, Strych, Ulrich, Meymandi, Sheba, Falcón-Lezama, Jorge Abelardo, Randall, Samuel, Hotez, Peter J., Lee, Bruce Y.

Journal:

Year:

2019

Language:

english

File:

PDF, 674 KB

english, 2019

47

The complete genome sequence of the nitrile biocatalyst Rhodocccus rhodochrous ATCC BAA-870

Frederick, Joni, Hennessy, Fritha, Horn, Uli, de la Torre Cortés, Pilar, van den Broek, Marcel, Strych, Ulrich, Willson, Richard, Hefer, Charles A., Daran, Jean-Marc G., Sewell, Trevor, Otten, Linda G

Journal:

Year:

2020

File:

PDF, 1.86 MB

2020

48

Characterization of the Alanine Racemases from Pseudomonas aeruginosa PAO1

Ulrich Strych, Hung-Chung Huang, Kurt L. Krause, Michael J. Benedik

Journal:

Current Microbiology

Year:

2000

Language:

english

File:

PDF, 190 KB

english, 2000

49

Enzymatic Synthesis of Magnetic Nanoparticles

Kolhatkar, Arati, Dannongoda, Chamath, Kourentzi, Katerina, Jamison, Andrew, Nekrashevich, Ivan, Kar, Archana, Cacao, Eliedonna, Strych, Ulrich, Rusakova, Irene, Martirosyan, Karen, Litvinov, Dmitri,

Journal:

International Journal of Molecular Sciences

Year:

2015

Language:

english

File:

PDF, 3.24 MB

english, 2015

50

SPIE Proceedings [SPIE SPIE BiOS - San Francisco, California, United States (Saturday 7 February 2015)] Nanoscale Imaging, Sensing, and Actuation for Biomedical Applications XII - Label-free monitoring of individual DNA hybridization using SERS

Cartwright, Alexander N., Nicolau, Dan V., Qi, Ji, Zeng, Jianbo, Zhao, Fusheng, Santos, Greggy M., Lin, Steven Hsesheng, Raja, Balakrishnan, Strych, Ulrich, Willson, Richard C., Shih, Wei-Chuan

Year:

2015

Language:

english

File:

PDF, 515 KB

english, 2015

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